Consider following polynomials: \begin{align} P_n(x)&=x^{2n-1}-\sum_{i=0}^{n-1}2\binom{2n}{2i+1}x^{2i} \end{align} for $n\geq 1$. Can we prove they are irreducible over $\mathbb{Q}$?
So first couple are $$x-4$$ $$ x^3-8x^2-8$$ $$ x^5-12x^4-40x^2-12$$ $$ \dots$$
For small specific values of $n$ we can prove it, for example for $x^3-8x^2-8$ we only need to check for linear factor, specifically for roots $\pm 1,\pm2,\pm4\pm 8$. With Maple I've verified more than first $600$ values of $n$ so far, all appear to be irreducible (using the irreduc function).
However for general $n$ I have no idea how to go about this, the Eisenstein criterion cannot be directly used, so I've tried substitutions like $P_n(x\pm 1)$, but it does not help.
Edit: Just out of curiosity, I have tried to change the polynomial a bit to see when it stops to be irreducible (again for small values of $n$, let's say to $100$) and I found it interesting that you can do quite a lot changes and it still remains irreducible. For example replacing the multiple of $2$ by other integers, or changing signs of the individual terms in sum, or even replace $2i+1$ in binomial coefficients with $2i$. What is going on?