Prevent multiple application instances after Windows restarts

Question

I have some applications, like Outlook, in my Startup folder so they run whenever my PC starts.

Now when Windows 10 installs updates and restarts itself, I come back to my desktop and have 2 instances out Outlook running. One from the Startup folder, and another because Windows restores any applications that were running at the time it shut down.

Is there any way to make it so only one instance will launch?

My PCs are all running Windows 10 1709 Pro, and exhibit this behavior for both Domain Accounts and personal Microsoft Accounts.

Answer 1

For Outlook, the shortcut in startup should include in the command line /recycle, which prevents opening a second window.

This is not a complete answer, I realize, just for Outlook.