Induction problems like this can be done mechanically by telescopy. Rewriting $\,f(n) = 2^n-n^2\,$ as a telescopic sum of its differences makes its positivity obvious, because each summand is $\color{#c00}{\ge 0}.$
$$\displaystyle\begin{eqnarray}n\ge 5\ \ \Rightarrow\ \ \ f(n) &=&\! f(5)\,+ \sum_{\large k\,=\,5}^{\large n-1}\ (f(k\!+\!1)-f(k))\\
\displaystyle\Rightarrow\ \ \ 2^n-n^2 &=& \ 7\ +\ \sum_{\large k\,=\,5}^{\large n-1}\, (\overbrace{2^{k}- (2k\!+\!1)}^{\large \color{#c00}{\ge 0}})\, >\, 0 \end{eqnarray}\qquad$$
That the overbraced term is $\color{#c00}{\ge 0}\,$ is obvious by induction (telescopic or not). Note that it fails for $\,n < 5,\,$ e.g. $\,f(4) = 0,\ f(3) = -1.\ $
For further discussion see my many posts on telescopic induction.