We say that the rectangle $PQRS$ is partitioned into 4900 squares by horizontal and vertical grid lines. There are $48$ horizontal grid lines not including $PQRS$, and $50$ horizontal grid lines including $PQRS$. Likewise there are $99$ vertical grid lines not including $PQRS$ and $101$ vertical grid lines including.
Let's look at how many squares the line segment $L=PT$ from $(0,0)$ passes to $(60,49)$. To this end, for each integer $i=0,1,2,\ldots, 59$, how many squares the line segment $L_i$ of $L$ from $(i,b_i)$ to $(i+1,b_{i+1})$ [whatever $b_i$, $b_{i+1}$ may be] passes through. [So $L=L_0+L_2+\ldots+L_{59}$.]
$1.$ If the line segment $L_i$ does not pass though a horizontal grid line, then the line segment $L_i$ passes only through $1$ square, the square w southwest corner $(i, [b_i])$, where in this answer $[x]$; $x$ a real
number, is defined to be the largest integer no larger than $x$.
$2.$ In general, if the line segment $L_{i+1}$ passes through $j$ horizontal grid lines, then the line segment $L_{i+1}$ passes through $j+1$ squares, unless $L_{i}$ ends at a corner that is.
$3.$ But as $\gcd(49,60)=1$ observe how the line segment $L$ from $(0,0)$ to $(60,49)$ starts and ends at a corner of a square but passes no corners in between. So none of $L_0, L_1,\ldots, L_{58}$ end at a corner.
$4.$ Finally, none of the squares are cut by more than one such $L_i$. Thus from 2. and 3. above the number of squares $L$ passes through is $59$ $+$ $48 +1=108$ [indeed $L_0+L_1+\ldots +L_{58}$ crosses in total $48$ horizontal grid lines none at the corners then finally $L_{59}$ ends at $(60,49)$ and cuts through exactly $1$ square--this we see via direct observation].
By similar reasoning as $1 ,2 ,3 ,4,$ above the number of squares the line segment $M=TS$ from $(60,49)$ to $(0,100)$ passes is $39 + 47 +2=88.$
So $108+88= 196$ total squares cut.