Key idea: Write all the fractions in the sum with the common denominator $2n!$
Let $M_i$ denote the product $$1\cdot2\cdot3\cdot\ldots\cdot(i-2)\cdot(i-1)\cdot(i+1)\cdot(i+2)\cdot\ldots\cdot(2n-1)\cdot2n$$ i.e., $M_i = \dfrac{2n!}{i}$ for $1 \le i \le 2n$. Each $M_i$ is clearly an integer.
We can write $H_{2n}$ by the common denominator $2n!$ as $$H_{2n} = \dfrac{\sum\limits_{k=1}^{2n} M_i}{2n!}.$$
Using Bertrand's Postulate, Let $p$ be a prime such that $n < p \le 2n$. Notice that this implies $2p>2n$, so no other multiple of $p$ is among $\{ 1,2,\ldots,2n \}$.
Now, in the fraction $\dfrac{\sum\limits_{k=1}^{2n} M_i}{2n!}$, notice that:
- The denominator $2n!$ is divisible by $p$.
- For $i \neq p$, the term $M_i$ is divisible by $p$.
- $M_p$ is not divisible by $p$.
Overall, in the fraction $\dfrac{\sum\limits_{k=1}^{2n} M_i}{2n!}$, the numerator is not divisible by $p$ but the denominator is divisible by $p$. Therefore, the fraction itself in not an integer. $\blacksquare$