Let $U\subset V$ be finite labeling sets, and $K:\mathbb S^1\to\mathbb R^3$ be a knot. Consider the configuration space with points labeled $U$ lying on the knot, to make this space connected we fix an isotopic class $[i]$of injections $U\to K(\mathbb S^1)$: $$C_{V,U}(K)=\{\text{injective maps }c:V\to \mathbb R^3: c\in [i]\} $$ note that $C_{V,U}(K)$ is a submanifold of $(\mathbb R^3)^{V\setminus U}\times(\mathbb S^1)^{U}$. My questions are
(1) Does the toopology of $C_{V,U}(K)$ depends on the knot $K$.(For example, if $K$ is the unknot and trefoil)
(2) Is there a good way to compute the homology of $C_{V,U}(K)$?(again, compute for the unknot and trefoil)
Any comment or reference is welcome!