I wanted to prove irreducibility of $f(X)=X^5 + 126X^4 + 57X^3 + 21X + 300$ over $\mathbb{Q}(\sqrt[19]{2})$.
When I saw this I realized Eisenstein proved it is irreducible over $\mathbb{Q}$ because $3$ divides every term and it's square does not divide $300$.
Clearly $x^{19}-2$ is the minimal polynomial of $\sqrt[19]{2}$ over $\mathbb{Q}$ and so $[\mathbb{Q}(\sqrt[19]{2}):\mathbb{Q}]=19$. If there were a root of $f$, say $\alpha\in \mathbb{Q}(\sqrt[19]{2}) $, we would have: $\mathbb{Q}\subset \mathbb{Q}(\alpha)\subset \mathbb{Q}(\sqrt[19]{2})$. Because $19$ is prime, we must have $\mathbb{Q}(\alpha)=\mathbb{Q}$ which is absurd as $f$ has no roots on $\mathbb{Q}$ or $\mathbb{Q}(\sqrt[19]{2})=\mathbb{Q}(\alpha)$.
But this is clearly absurd, because $\deg(\min(\mathbb{Q},\alpha))\leq 5$, but it should be $19$. Therefore $f$ really has no roots over $\mathbb{Q}(\sqrt[19]{2})$. However this doesn't really help to prove $f$ is irreducible, because we must consider all other possible non trivial decompositions...