the argument's first two premises and conclusion are false, so it is valid.
No. The arguments ∃x (x^2 < 0); therefore, 1≠1 and ∀x∀y x=y; therefore, 1≠1, each of which also has a false premise and false conclusion, are invalid, because each has a true premise and false conclusion in complex analysis, and when the universe is restricted to $\{3\},$ respectively.
(The above tells us that a false premise also doesn't automatically validate an argument. However, since every conditional with an unsatisfiable antecedent is logically true, an inconsistent set of premises does invalidate an argument.)
the argument's second premise and the conclusion are inconsistent with each other, so it is invalid.
No. The argument 1=1 and 1≠1; therefore, 1=1 has a premise and conclusion in contradiction, and (as explained above) is valid.
Let $x,y,z$ be integers greater than $1,$ and define
$p(x,y)$: $x$ is a factor of $y$
$q(x,y,z)$: $z = \operatorname{GCF}(x,y)$
$r(x)$: $x$ is prime.
$$ \forall x\exists y\;(P(x,y) \implies R(x))\\ \forall x\forall y\forall z\;(\neg Q(x,y,z))\\\exists x\forall y\;(P(x,y) \vee R(x))\\\therefore\quad\forall y\exists x\exists z\;Q(x,y,z).$$
The following countermodel shows that the given argument's logical form can have a false conclusion without any false premise; so, the given argument must be invalid:
\begin{align}&\text{discourse domain}=\mathbb R\\P(x,y)\quad&{:\Leftrightarrow}\quad x+y=x+y\\
Q(x,y,z)\quad&{:\Leftrightarrow}\quad x+y+z\ne x+y+z\\
R(x)\quad&{:\Leftrightarrow}\quad x=x.\end{align}
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You can validly reach false conclusions from every false premise, for instance, $2=4,$ therefore $2+2=4+2,$ therefore $4/2=6/2,$ therefore $2=3.$
@David So is the argument you gave in your explanation valid? If so, it means that arguments with false premises which reach false conclusions are valid arguments, right?
No, while David's example argument is certainly valid under arithmetic axioms, it isn't in itself logically valid (see this by defining 2=4 and x+y=y and x/y=y, noting that + and / are arithmetical rather than logical operators).
An argument being (logically) valid just means that its corresponding conditional is valid, that is, true regardless of the context. After all, argument validity depends just on argument form, and is independent of the argument's specific content.