Let $X,Y$ be smooth algebraic varieties over $\mathbb{C}$, $M^\bullet\in\mathsf{D}^b_{\text{coh}}(\mathcal{D}_X)$, $N^\bullet\in\mathsf{D}^b_{\text{coh}}(\mathcal{D}_Y)$, and denote by $\mathrm{D}_X$ the Verdier duality functor over $X$.
I wonder if it's true that $\mathrm{D}_{X\times Y}(M^\bullet\boxtimes N^\bullet)=\mathrm{D}_X(M^\bullet)\boxtimes \mathrm{D}_Y(N^\bullet)$.
This is true for constructible sheaves, so Riemann-Hilbert implies it at least for regular holonomic modules. (I can explain it if someone wants.) But there should be a direct proof in this generality.
(I've put complex geometry as a tag because the same result should hold for D-modules over complex varieties as well and, I hope, with the same proof.)