Consider the two-dimensional complex Lie algebra defined by $[X,Y]=iY$. Are there non-trivial representations where $X$ and $Y$ are Hermitian (possibly unbounded)? By the way, the above is the unique two-dimensional non-abelian Lie algebra up to isomorphism.
Note such representations cannot be finite-dimensional, in short because $Y$ raises and lowers the eigenvalues of $X$ by $i$, so $X$ cannot be Hermitian. More precisely, if $X$ has eigenvector $v$ with eigenvalue $x \in \mathbb{R}$, then $XYv=(iY+YX)v=(i+x)Yv$, so either $Yv=0$ (and by extension $Y=0$) or else $X$ has an eigenvector $Yv$ with eigenvalue $x+i \not\in \mathbb{R}$, a contradiction.
Alternatively, re-defining $X \mapsto iX, Y \mapsto iY$, I am interested in reps of $[X,Y]=Y$ with $X,Y$ anti-Hermitian.