Meanwhile I got it...
Square Root
It is a well-know result:
$$Q\in\mathcal{B}(\mathcal{H}):\quad Q=Q^*$$
The range includes:
$$\mathcal{R}Q=\mathcal{D}(1+N^*N)=\mathcal{D}N^*N$$
One has the bound:
$$\langle Q^{-1}\psi,\psi\rangle=\langle(1+N^*N)\psi,\psi\rangle=\|\psi\|^2+\|N\psi\|^2\geq0$$
So the numerical range:
$$\mathcal{W}(Q^{-1})\geq0\implies\mathcal{W}(Q)\geq0$$
For bounded operators:
$$Q\in\mathcal{B}(\mathcal{H}):\quad\sigma(Q)\subseteq\overline{\mathcal{W}(Q)}$$
Thus the square root exists:
$$\sqrt{Q}\in\mathcal{B}(\mathcal{H}):\quad\sqrt{Q}=\sqrt{Q}^*$$
Especially range and kernel:
$$\mathcal{H}\supseteq\overline{\mathcal{R}\sqrt{Q}}\supseteq\overline{\mathcal{R}Q}=\mathcal{H}$$
$$(0)\subseteq\mathcal{N}\sqrt{Q}\subseteq\mathcal{N}Q=(0)$$
(This is basic so far.)
Operator
One has the bound:
$$\|NQ\varphi\|^2=\langle N^*NQ\varphi,Q\varphi\rangle\leq\langle N^*NQ\varphi,Q\varphi\rangle+\langle Q\varphi,Q\varphi\rangle=\langle\varphi,Q\varphi\rangle=\|\sqrt{Q}\varphi\|^2$$
The operator is closed:
$$\sqrt{Q}\in\mathcal{B}(\mathcal{H}):\quad\quad N=\overline{N}\implies Z=\overline{Z}$$
By uniform extension:
$$\|Z\restriction_{\mathcal{R}\sqrt{Q}}\|\leq1\implies Z\in\mathcal{B}(\mathcal{H})$$
Especially the range lies in:
$$\mathcal{D}Z=\mathcal{H}\implies\mathcal{R}\sqrt{Q}\subseteq\mathcal{D}N$$
(Domain is unclear a priori!)
Polynomials
Here regard elements:
$$\varphi,\chi\in\mathcal{D}N=\mathcal{D}N^*$$
Exploit the selfadjoint inverse:
$$\langle NQ\varphi,\chi\rangle=\langle Q\varphi,N^*(1+N^*N)Q\chi\rangle=\langle Q\varphi,(1+N^*N)N^*Q\chi\rangle=\langle QN\varphi,\chi\rangle$$
Thus a calculation reveals:
$$\langle\sqrt{Q}N\varphi,\chi\rangle=\lim_n\langle Q_nN\varphi,\chi\rangle=\lim_n\langle NQ_n\varphi,\chi\rangle=\lim_n\langle Q_n\varphi,N^*\chi\rangle=\langle N\sqrt{Q}\varphi,\chi\rangle$$
Hence on operator level:
$$N1=1N\quad NQ\supseteq QN\quad NQ^k\supseteq Q^kN\quad N\sqrt{Q}\supseteq\sqrt{Q}N$$
(The analogous hold for adjoint.)
Normality
Formally the adjoint acts as:
$$\langle Z\varphi,\psi\rangle=\langle\varphi,\sqrt{Q}N^*\psi\rangle\quad(\psi\in\mathcal{D}N^*)$$
Regard dense elements:
$$\varphi\in\mathcal{R}\sqrt{Q}\subseteq\mathcal{D}N=\mathcal{D}N^*$$
Remind also that:
$$\sqrt{Q}\varphi\in\mathcal{R}Q=\mathcal{D}N^*N=\mathcal{D}NN^*$$
Thus one derives:
$$Z^*Z\varphi=\sqrt{Q}N^*N\sqrt{Q}\varphi=\sqrt{Q}NN^*\sqrt{Q}\varphi\\
=N\sqrt{Q}N^*\sqrt{Q}\varphi=N\sqrt{Q}\sqrt{Q}N^*\varphi=ZZ^*\varphi$$
Concluding normality.