Is there a $O(n^2)$ algorithm to resolve isomorphism between two weighted $n$-vertex graphs? This is a much easier problem than graph isomorphism.
Basically take an real edge weight set $\{w_1,\dots,w_s\}$ where $s=\Omega(n^\alpha)$ where $\alpha\in[0,2]$ and the edge weights are picked uniformly. We can think of the second graph as being generated as follows: Input the weighted first graph to a black box and the black box returns the second graph based on some mechanism.
For every $n$ fix a set of weights.
For every input graphs you assign weights uniformly from a distribution. Then you feed in the input graph, weights and the second graph to the black box and the black box returns you the weighted second graph. Then you have to decide isomorphism on these two weighted graphs. So the probability is over all assignments of weights (the weight set is fixed for every $n$ in some worst case way). If this has an algorithm that is in $\mathsf{BPP}$ then in theory it should be conjecturally derandomizable.