Ultimately, I'm interested in non-Archimedean local fields $F$, and am happy to take $\text{char}(F)=0$, and just focus on split $PGL_n(F)$. I suspect that the theory "more less" reduces to (smooth) representations of $GL_n(F)$ whose irreducible constituent have trivial central character. Maybe there's even an equivalence of categories?
It seems to me that there would be some things to check though, such as making sure one can pass between representations of the groups and preserve smoothness, etc. Also, I would like to know/hope that the Levis and parabolic induction "play nice" with each other (take that vague statement as you will).
Has anyone worked this out somewhere?