I know that exhaustive search was done to test numbers up to 2^68.
This seems like a big number but when looking at Collatz function as a Turing machine manipulating some input bit sequence, only sequences up to 68 bits were tested. Maybe something interesting happens with numbers that have ~1000000 bits (that is in range ~2^1000000)?
I couldn't find any project searching for Collatz counter-examples this way, do you know about any?
Also, when checking random numbers, are there any results that prove that only some numbers can become such counter-examples? I found somewhere that it is sufficient to check numbers x that (x mod 6) = 2 but I don't know if it was rigorously proven.