Take a non-measurable set $E$ and for each $e\in E$ let $\chi_{\{e\}}$ be the characteristic function of the set $\{e\}$. Then the supremum of the (uncountable) family $\{\chi_{\{e\}}:~e\in E\}$ is the characteristic function $\chi_E$ of the set $E$, which is not measurable and therefore nor Borel measurable.
Edit
$\chi_E$ is the supremum of the family since it is greater or equal than any function of the family, and is the smallest function with such property.
$\chi_E \geq \chi_{\{e\}}$ for all $e\in E$; indeed,
- if $x\in E$, then $\chi_E(x) = 1 \geq \chi_{\{e\}}(x)$ for all $e\in E$;
- if $x\notin E$, then $x\neq e$ for all $e\in E$ and hence $\chi_E(x) = 0 = \chi_{\{e\}}(x)$.
$\chi_E$ is the minimal such function, in that if $f(x)<\chi_E(x)$ for some $x$, then there exists $e\in E$ such that $f(x) < \chi_{\{e\}}(x)$; indeed,
- if $x\in E$, then $\chi_x$ belongs to the family and $f(x) < \chi_E(x) = 1 = \chi_{\{x\}}(x)$;
- if $x\notin E$, then $f(x) < \chi_E(x) = 0 = \chi_{\{e\}}(x)$ for all $e\in E$.